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INTRODUCTION In 1970, Laugier and Hunziker reported five cases of unusual acquired macular hyperpigmentation on the lips and oral mucosa, and two of these patients displayed longitudinal pigmented streaks on the nails[1]

(PubMed) Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA

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In addition to the well-known effects of TSHR antibodies on fibroblasts in Graves disease (GD), studies speculate on a role of anti-thyroid antibodies in cancer