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The hypothetical estimand (on-treatment without rescue medication) showed a statistically significant difference between the 16 mg and 2 mg groups, for both the HbA1c reduction and a weight loss with -0.5 percentage points (95 % CI: -1.0 to -0.1

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If changing your regular injection day, ensure at least 72 hours between doses

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Protocol 2: intensive 10-day cycle Goal: Concentrated telomerase activation with reduced injection frequency Duration: 10 days active, then 4-6 months off Schedule: Days 1-10: 10 mg epitalon subcutaneously, once daily at bedtime Days 11-180: Off cycle Repeat cycle 1-2 times per year Reconstitution: 10 mg vial plus 1 mL bacteriostatic water equals 10 mg/mL