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The trial protocol employed a gradual titration schedule specifically to mitigate gastrointestinal tolerability issues, a strategy consistent with approaches used for semaglutide and tirzepatide in clinical practice

Kieber JJ, Schaller GE (2018) Cytokinin signaling in plant development

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We assessed the quality of the studies with the risk of bias assessment tool for randomized controlled trials and the Risk of Bias in Non-randomized Studiesof Interventions (ROBINS-I) tool for nonrandomized trials

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Spearmans correlation was performed for analysis between the quantitative covariates and the outcome