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Solid-phase peptide synthesis of D-amino acid chains of this length requires specialized reagents (D-Fmoc amino acids are significantly more expensive than their L-counterparts), extended synthesis times, and careful quality control to ensure correct sequence and sufficient purity

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10.1016/j.yexcr.2021.112740 30 DominiciM.Le BlancK.MuellerI.Slaper-CortenbachI.MariniF.KrauseD.et al (2006)

There is a pressing need for safer alternatives for antibiotics, particularly those that are natural, non-toxic, and do not cause resistance