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However, stores can run low due to a number of factors, including a genetic inability to produce sufficient amounts

189 Further, ME1 treated with the inhibitor (piperazine-1-pyrrolidine-2,5-dione) has little effect on normal rat intestinal epithelial cells but strongly suppresses human CRC cell growth by targeting ME1 NADP + -binding site and reducing the NADPH level

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and its antioxidant capacity

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