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Administration of GLP-1 or GLP-1RAs (including exenatide, geniposide, liraglutide, lixisenatide, and semaglutide) enhances neurogenesis in the dentate gyrus, hippocampus, olfactory bulb, and medial striatum in animal models, while modulating apoptotic pathways and increasing animal survival under extreme factors [24]

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As of this writing, the FDA has not yet formally published the updated Category 2 list following Secretary Kennedy's February 27, 2026 announcement

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Because of its antioxidant and antiinflammatory properties, GHK is a promising peptide for use in the treatment of age-related neurodegenerative conditions