Documented Long-Term Side Effects of Corticosteroids Bone loss and fractures due to calcium and vitamin D depletion and impaired osteoblast activity (2) Blood sugar dysregulation and steroid-induced diabetes through increased insulin resistance and gluconeogenesis (3) Muscle wasting and impaired connective tissue repair from protein catabolism and suppressed synthesis (4) Weakened immunity, delayed healing, and prolonged infections related to micronutrient depletion and immune suppression (5) Weight gain, mood changes, and insomnia driven by hormonal and circadian disruption (6,7) Abnormal blood lipids, hypertension, and increased cardiovascular risk , including heart attack, with long-term use (8) Thinning skin and easy bruising from collagen breakdown and connective tissue loss (9) Psychiatric effects , including anxiety, irritability, depression, andin severe casessteroid-induced psychosis, particularly at higher doses or with prolonged exposure (10) Even short-term corticosteroid use can cause side effects in susceptible patients

B12 injections can provide a natural energy boost by aiding in the conversion of food into usable energy
[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Mansour HH, El kiki SM, Ibrahim AB, Omran MM
Molecular replacement was performed in Phenix using PDB IDs 7S22 for WD40 mutants and 4J79 for WD40 in complex with S hepta-peptides 43,61,79
Birnbaum ZW
B12 shots may support weight loss by boosting energy levels and metabolism, especially in individuals with a B12 deficiency