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Shibata M, Nakamuta H, Abe S, Kume K, Yoshikawa I, Murata I, Otsuki M

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Kriebardis, Nikolaos Papadopoulos, Evangelos Koustas, Panagiotis Sarantis, Spilios Manolakopoulos, Melanie Deutsch International Journal of Molecular Sciences .2025

The medications work through different pathwaysHRT replaces hormones while semaglutide regulates appetite and insulin sensitivity

For the phase III clinical program, a total of eight studies were initiated that investigated the efficacy and safety of tirzepatide in comparison to various other established antidiabetic medications in T2D either in monotherapy, combination with metformin as baseline therapy, or metformin and insulin glargine as a baseline

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