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In order to monitor the intracellular translocation of agonists, as well as GLP-1Rs, we used fluorescently labeled exendin-4, exendin-phe1, and exendin-asp3 conjugates, with fluorescein isothiocyanate (FITC) at position K12, which we previously found useful for labeling GLP-1R 28
Derlin T, Tornquist K, Mnster S, Apostolova I, Hagel C, Friedrich RE, et al
Actions are dependent upon peptide type, dose and method of administration
Potential side effects include abdominal discomfort, constipation, diarrhea, nausea, vomiting, fatigue, headache