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The key pathways including lipotoxicity and oxidative stress (involving NLRP3 inflammasome, MAPK, PI3K/Akt, and RAAS signaling), inflammation (via NF-B, NLRP3 inflammasome, JAK-STAT, Toll-like receptor, and cGAS-STING pathways), and fibrosis/ECM production (driven by TGF-, Wnt, RAAS, and Notch signaling) have been identified and reported in CKD progression [235]

CD38 in hematopoietic malignancies

Although ultrasound-guided injections are more commonly used in human clinical settings, their application in this animal study reflects an advancement in experimental methodology [1]

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Bronchial thermoplasty: reappraising the evidence (or lack thereof)