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doi: 10.1042/CS20171330

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Potential Links between Impaired One-Carbon Metabolism Due to Polymorphisms, Inadequate B-Vitamin Status, and the Development of Alzheimer's Disease

A pilot human trial in Nature Communications (2022) showed that NAD+ precursor supplementation improved biological age markers and activated anti-aging pathways in humans

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10.1186/s13287-022-02742-1 99 SiddiquiM