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J Biol Chem 276 , 73977403, doi: 10.1074/jbc.M008631200 (2001)

Without enough B12, oxygen delivery is impaired, leading to low energy levels and fatigue

However, the review noted that studies in truly alcohol-dependent animals remain limited, and many models have focused on reinforcing effects rather than continued drinking despite negative consequences

The purpose of lab review is not to blame the patient