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The oxidative damages of biomolecules specifically of DNA due to the accumulation of hydroperoxides and other ROS ultimately lead to the loss of cell viability or cell death through various death mechanisms like apoptosis, autophagy, necrosis, ferroptosis, and mitotic catastrophe (Fig
They give insights into metabolic health, growth hormone regulation, and body composition
This review synthesizes evidence from randomized controlled trials and meta-analyses published up to 2024, evaluating the efficacy and safety of commonly used supplements such as myo-inositol, vitamin D, omega-3 fatty acids, selenium, and coenzyme Q10
The wide range of side effects is the result of chemotherapeutics targeting a wide range of cell-cycle dependent mechanisms, and often specifically rapidly dividing cells
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