Additionally, fat tissue serves as a site of oestrogen production through peripheral aromatisation of androgens, which may paradoxically affect hormonal fluctuations during the menopausal transition
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Those with deeper skin tones may need 6 to 12 months of consistent supplementation
As for how long the treatment lasts, the doctors we spoke with agreed that it could be an indefinite arrangement, with the hope that, with proper lifestyle changes, a child may be able to stop taking the medication eventually
While phase 2 and phase 3 trials provide substantial data, they involve hundreds to thousands of participants over months