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13.4 Avoiding Abrupt Discontinuation Sudden cessation may result in rebound hyperglycemia or loss of therapeutic benefits

The disease has no cure and often leads to secondary biliary cirrhosis, portal hypertension, hepatic failure, and cholangiocarcinoma if hepatic transplantation is not performed

What to inject: 3.0 mL reconstitution: 30 units once weekly 2.0 mL reconstitution: 20 units once weekly 4.0 mL reconstitution: 40 units once weekly What to expect: Weight loss accelerates

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