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HFD differentially methylates vitamin D metabolism enzyme genes and VDR To identify the gene-specific methylation of CpG island of vitamin D metabolism genes and VDR, we adapted a digestion-based gene-specific PCR methylation assay

The researchers measured impulsiveness using the Barratt Impulsiveness Scale, a validated psychological tool that captures everyday impulsive tendencies like acting without thinking or struggling to resist urges. After 3-6 weeks of tirzepatide treatment, participants reported feeling significantly less impulsive than those who received the placebo

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