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DISCUSSION It is unexpected to find carnitine and acylcarnitines remaining in RBC because of the absence of mitochondria and because they are energetically independent of fatty-acid oxidation, with no demand for classical carnitine-mediated fatty-acid transport

Therefore, estimation of GLP-1 secretion in mice cannot be made by measuring intact GLP-1(936)NH 2 levels, but should instead be assessed using C-terminally directed methods capable of measuring the fragment FIAWLVKGR [GLP-1(2836)NH 2 ], which was identified in plasma in vivo

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