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It also serves to keep the hemoglobin iron in the ferrous state by reducing peroxides that undergo a reaction in which they extract an electron from ferrous iron, converting it to ferric iron, which impairs hemoglobin function
The transformed Pichia pastoris cells are induced to express these proteins by adding 0.5% methanol daily to the culture, respectively
A.CobosA.DiazO.AguileraJ
They also play a role in maintaining physiological homeostasis, such as cognition, blood pressure, feeding behavior, water balance, glucose metabolism, pain, and response to stress [7]
Simultaneously, catalytically produced hydrogen peroxide (H 2 O 2 ) activates the protein transient receptor potential melastatin 2 (TRPM2) ion channel, promotes calcium influx, activates macrophages, and induces systemic immune response (Fig