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In the latest JAMA Medical News podcast, Jennifer Abbasi interviews Rita Kalyani, MD, about investigational therapies including retatrutide, a triple agonist showing high efficacy for glycemic control and weight loss, and new oral options like orforglipron

Antioxidative potential of a combined therapy of anti TNFalpha and Zn acetate in experimental colitis

The GLP-1s also protect the kidneys, especially in diabetes, and a review of the FDAs adverse reporting system suggests that GLP-1s may protect against renal damage from lithium in the long term

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Early assessment helps guide safe recovery and prevent complications like post-concussion syndrome (PCS) when headaches and other symptoms persist beyond the typical healing window

Lippman et al