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Theres uncertainty around the effectiveness of microdosing compounded versions of GLP-1s and a lack of research on the safety of this method

Most users inject into their abdomen or thigh once per week

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Back Carlsson, LMS, Carlsson, B, Jacobson, P, et al (12 July 2023) 'Life expectancy after bariatric surgery or usual care in patients with or without baseline type 2 diabetes in Swedish obese subjects', International Journal of Obesity (London) , 47/10

Oral Semaglutide and Cardiovascular Outcomes in Patients With Type 2 Diabetes

The authors attributed this increased risk to delayed gastric emptying, resulting in greater gastric volume and intra-gastric pressure and thereby contributing to acid reflux