Such a robust fibrosis can be induced in rodents with prolonged or repeated exposure to certain chemicals (carbon tetrachloride, alcohol, tetrachlorovinphos, diallylphthalate), dietary lipotrope deficiency, or chronic hepatitis secondary to persistent infection (Ward 1997)
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Stanley S, Moheet A, Seaquist ER
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Subjects underwent semen analysis at baseline and 3-months after therapy with semen being obtained by masturbation after a sexual abstinence of 3-5 days