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The activation of ERK serves a critical role in anti-apoptotic processes (80)
Imaging: For injuries, imaging can document structural changes over time
It has been reported that NOX4 directly interacts with TLR4, which is pivotal for LPS-mediated NF-B activation
The ferroptosis inhibitor liproxstatin-1 has been shown to reverse iron accumulation, endothelial damage, and increased atherosclerosis in Jak2VF chimeric mice and VFEpoR mice, 539 indicating a potential therapeutic target for mitigating erythrocytic ferroptosis-mediated cardiovascular risk
doi: 10.3389/fphar.2025.1528208 Received 14 November 2024 Accepted 02 April 2025 Published 10 April 2025 Volume 16 - 2025 Edited by Yanggan Wang, Wuhan University, China Reviewed by Yi Zhu, Chengdu University of Traditional Chinese Medicine, China Baonian Liu, Shanghai University of Traditional Chinese Medicine, China Updates Copyright 2025 Chen, Fu, Zhou and Wu
