In challenge infections using WT UTI89 and UTI89 hlyA strains in nave, resolved and sensitized mice, we observed that hlyA infection, which does not activate caspase-1-mediated pyroptotic cell death, showed significantly increased bacterial burdens in sensitized mice compared with WT mice, whereas no differences were observed in nave and resolved mice (Fig
Finally, the authors of the previously mentioned review, Adeoye O et al , went on to state that glutathione (GSH) may have an important impact on is autoimmune issues
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