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Glutathione levels also decrease as we age and our need for supplemental glutathione increases significantly

Over the past decade, gemcitabine has remained the standard first-line therapy for advanced PDAC, primarily exerting its effects by inducing DNA damage, promoting ROS accumulation, and triggering ferroptosis [153]

When glutathione is low, the body may struggle to maintain its natural detoxification pathways and immune responses

doi: 10.1186/s13045-019-0720-y 145 HuMZhangYMaSLiJWangXLiangMet al

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