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The peptide makes that deficit more effective at mobilizing fat, but eating at maintenance or surplus won't produce results

Draft guidance for industry

When AOD-9604 Fat Cell Targeting is Most Effective The AOD-9604 approach to fat cell targeting is particularly well-suited for individuals who have achieved good metabolic health through diet and exercise but struggle with stubborn fat deposits, those seeking selective fat loss without appetite suppression or systemic metabolic changes, athletes or active individuals who need to maintain training capacity and muscle mass during fat loss phases, individuals who cannot tolerate or are contraindicated for GLP-1 agonists or growth hormone therapy, and those seeking a research-backed, clinically-studied option with established safety data from human trials

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GHK-CU cycling strategies Cycling involves planned periods of use alternating with breaks

This could lead to very different prevalence estimates for a number of reasons, which are discussed here