By controlling intracellular and extracellular ROS levels, the Trx system regulates the survival and performance of immune cells, including immune cell polarization, immune tolerance, metabolic reprogramming, cytokines production, and chemotaxis [43, 44]
[DOI] [PubMed] [Google Scholar] 182.Volpi-Abadie J., Kaye A.M., Kaye A.D
Challenges, progress, and prospects of developing therapies to treat autoimmune diseases
Estrogen Receptor Functions and Pathways at the Vascular Immune Interface
Osteoclast-osteoblast imbalance leads to local bone resorption and therefore to severe deformities, higher risk of DFUs, disability risk for amputation [155]
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