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During the 30-week double-blind placebo-controlled period of the glycemic control trial in pediatric patients 10 years of age or older with type 2 diabetes mellitus [see Clinical Studies (14.5)], 30/61 (49%) of MOUNJARO-treated pediatric patients developed anti-tirzepatide antibodies

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Meanwhile, even though your Folic Acid status is great and red blood cells appear normal, not having enough B12 will cause homocysteine to build up, leading to neurological damage and changes in DNA function without you realizing it until symptoms set in

Drugs (2024)

[14] The therapy is used off-label based on emerging science and clinical experience