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Several brain regions such as prefrontal cortex (PFC), nucleus accumbens (NAc), ventral tegmental area (VTA), hippocampus (HPC) and amygdala are interconnected with each other via dopaminergic, serotonergic, glutamatergic and GABAergic neurons, which comprise the reward circuit (35, 36)

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Decline of these detoxification pathways, scientists say, are causally linked to cardiovascular disease, diabetes and cancer, some of the primary causes of death in the developed world

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Parkinsons affects the central nervous system, causing cellular damage in the brain that leads to a severe drop in dopamine levels

Glutathione 250mg alone, however, was not significantly superior to placebo.52 Another recent RCT (n=46) reported decreased skin pigmentation following an 8-week regimen of 600mg of glutathione, 50mg of -lipoic acid, and 4mg of zinc.53 Even better results were observed for oral glutathione combined with topical 2% glutathione