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In this mini-review, we critically examine both clinical and experimental evidence, with emphasis on the direct effects of glucagon-like peptide-1 receptor agonists on endothelial function

For instance, chronic constipation may lead to haemorrhoids or anal fissures, whilst severe diarrhoea could cause irritation of the rectal mucosa

There is no end date for eligibility to submit a data-sharing request for these data

Generalized anxiety disorder is associated with prolonged sleep-onset latency, frequent nocturnal awakenings, and reduced slow-wave sleep due to elevated corticotropin-releasing factor activity and hyperactivated HPA axis tone

We do not present it as a stand alone miracle but as a support for biological correction of appetite dysregulation that often underlies chronic weight challenges

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