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Bioavailability refers to how much of a nutrient your body can actually absorb and use

Summary: Metformin and semaglutide work through complementary mechanismsmetformin reduces liver glucose production and improves insulin sensitivity, whilst semaglutide enhances insulin secretion, suppresses appetite, and slows gastric emptyingproviding superior blood sugar control and weight loss when used together

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In the documented protocol, daily during the 4-week activation phase, then 5/week for weeks 58, then 23/week for maintenance

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