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Water, Glycerin, PEG-8, Niacinamide, Butylene Glycol, Methylpropanediol, 1,2-Hexanediol, Betaine, Glycereth-26,m Bis-PEG-18 Methyl Ether Dimethyl Silane, Polyglyceryl-10 Laurate, Bifida Ferment Lysate, Methyl Gluceth-20, Panthenol, Squalane, Glucosylrutin, Hydrogenated Lecithin, Carbomer, Caprylic/Capric Triglyceride, Tromethamine, Xanthan Gum, Propanediol, Flavor, Ethylhexylglycerin, Glutathione(500ppm), Adenosine, Ceramide NP, Sodium Phytate, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Dextrin, Theobroma Cacao (Cocoa) Extract, Beta-Glucan, Cyanocobalamin, Sodium Hyaluronate Crosspolymer, Tocopherol, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Soluble Collagen, Hyaluronic Acid, Sodium Acetylated Hyaluronate, Sodium Stearoyl Glutamate

In the protein processing in the ER pathways, 2 genes ( Bcsec62 and Bcero1 ) related to correct or misfolded protein processing and 14 genes ( BCIN_02g04920, BCIN_15g04190, BCIN_15g02550, Bcubc6, Bcfes1, Bcotu1, BCIN_10g00300, Bcufd2, BCIN_03g09290, Bcsec63, Bcdsk2, Bcrad23, Bcpng1 , and BCIN_08g04560 ) from the ER-associated degradation (ERAD) were significantly upregulated in our study (Supplementary Table 7)

doi: 10.1007/s10534-011-9504-8

Cell viability was determined using the Alamar Blue reduction bioassay 7,10,47

Supplementary material The Supplementary Material for this article can be found online at: References 1 AltintasO.Ozgen AltintasM.KumasM.AsilT

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