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Viability assay was also performed with combination of RSL3 and Fer1 (5 M) or ZVAD (50 M)

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In contrast, after the addition of SB431542, a TGF signalling inhibitor, to the high-glucose medium, -SMA expression in PSCs decreased to a nearly undetectable level

However, in scenarios where the FOXO4 is linked with the DRI peptide, it is suggested that this binding may not occur, potentially allowing p53 to interact with DNA and facilitate the continuation of the cell cycle toward programmed death

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