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Another group utilized a Cre-lox P system where Cre recombinase was placed under the control of the interferon-responsive Mx promoter and reported similar results using 12-week-old animals (Sjogren et al., 1999)

Pharmacological advances in mitochondrial therapy

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

Additionally, the model accommodates repeated oral gavage necessary for THC administration

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