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What Ive Learned from Practice Over the years, several themes keep showing up: When we treat ED as a vascular and systemic issue first, outcomes improve

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In the central nervous system (CNS), bacterial-derived SCFAs contribute to normal maturation of microglia via the free fatty acid receptor 2 (FFAR2) as a SCFA receptor (69)

However, starting at low doses and ramping up slowly to higher doses is a proven strategy for lessening the severity of these side effects