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We visualized the regulated sites as a function of treatment by hierarchical clustering of the averaged phosphorylation site intensities per replica, which grouped likely substrates and targets according to the kinase inhibited (Fig

Semaglutide's effects depend on GLP-1 receptor signaling in the brain and pancreas, while glutathione exerts its effects intracellularly through redox balance

Haptoglobin and hemopexin infusion efficiently activates the Nrf2/HO-1 axis and inhibits inflammation and vaso-occlusion in murine sickle cell disease

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Aging Cell 21 , e13589 (2022)