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Several surgical options are available: ablation of the ulcerative lesions in the bladder, resection of ilioinguinal and iliohypogastric nerves, reconstructive surgery, and cystectomy.11 In a review of 450 patients with severe interstitial cystitis who had undergone an operation, surgery was associated with a complication rate of 26.5% with an overall mortality of 1.3%.12 History of BPC-157 In 1993, Predrag Sikiri, MD, PhD, of Croatia isolated the peptide Body Protective Compound 157 (BPC-157) from human gastric juice.13 In animal studies, BPC-157 has been shown to have many restorative properties.14 It can help with repairing tendons, ligaments, muscles, nerves, bone fractures, teeth, and corneas and promote recovery from traumatic brain injury.15-25 BPC-157 has been shown to reduce inflammation in different animal models.26,27 The pharmacokinetics, excretion, metabolism, and distribution profiles of BPC-157 were performed in rats and in beagle dogs

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For broader context on regenerative pathways and compound interactions, see our Healing & recovery research guide

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