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Description

Understanding the mechanism helps set expectations

PMID: 147 DengJKTanY

For total protein determination, tissue lysates were solubilized in Laemmli buffer (BioRad, Hercules, CA, USA) and separated by SDS-PAGE using precast TrisHCl gels (BioRad, Hercules, CA, USA)

A significant focus was on developing inhibitors of insulin-regulated aminopeptidase (IRAP), a protein identified as the AT4 receptor, with the goal of enhancing metabolic stability and BBB permeability