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If you expose yourself to sun after a loading phase (typical protocol found online), all that built up melanin will oxidize in the exposed areas leading to a dramatic tanning effect and thus uneven tanning

The 12-week study by Leyden and colleagues that anchors most topical evidence used a once- or twice-daily facial application

Free Radic Biol Med 44(6):921937 Go YM, Jones DP (2010) Redox control systems in the nucleus: mechanisms and functions

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