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If the vial seems pressurized in the other direction (pushing the plunger back when you insert the needle), you may have injected too much air during reconstitution

The GLP-1RA may be a choice of therapy when weight control and avoidance of hypoglycemia are important, and patients with high risk of cardiovascular disease might also favor choosing GLP-1RA

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Surgery is the last option

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It occurs in less than 1% of patients and is typically caused by the needle accidentally nicking a small blood vessel under the skin