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As more research emerges, the promising results seen so far could lead to a new standard in weight loss treatments

& Furness, S

With metformin there was a decrease in large for gestational age, a significant decrease in insulin required, a small decrease in HbA1c and about a 2 kg decrease in weight gain

In clinical practice, SGLT2 inhibitors are often initiated first due to their oral administration and broader reimbursement, with GLP-1 receptor agonists subsequently added to address persistent hyperglycemia, excess body weight, or residual albuminuria [84,85]

Blurred vision and visual impairment were relatively high with both oral and injectable drugs

Sleep quality directly influences hunger-regulating hormones, including leptin and ghrelin, and poor sleep has been shown to blunt the effectiveness of both dietary and pharmacological weight management strategies