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For example: Fatigue, unexplained weight loss, or abdominal pain may indicate liver disease or cancer Easy bruising, night sweats, or feeling full quickly (early satiety) may suggest a myeloproliferative disorder Swelling in the legs, reduced urine output, or persistent nausea may point to kidney disease In cases of very high B12 from injections (not oral supplements), some people have reported headache, nausea, diarrhea, facial flushing, or skin rash

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54 The main drawback to IV therapy with glutathione is that it requires clinic visits, whereas glutathione injections can be administered at home if your doctor prescribes them

[144] Glutathione is thought to be non-toxic to humans, [144] although one study found a 5 g oral daily dose was associated with GI irritation and sulfur odor