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Patients with mild to moderate renal impairment generally do not require dose adjustment, but closer monitoring may be warranted, particularly for signs of gastrointestinal adverse effects that could lead to dehydration and worsening renal function

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B12 supports nervous system health and is important in making the myelin sheath, which transmits the nerve impulses

Hypoxia induces production of pro-angiogenic factors leading to enhanced, rapid and chaotic blood vessel formation

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