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The study also highlighted AOD9604s influence on fat metabolism and energy expenditure, and its interaction with 3-adrenergic pathways [2]

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Consequently, OCR is then represented by the R 2 reaction flux, as shown in Equation (6)

doi: 10.1073/pnas.1416940111

In the kidney, elevated ROS levels contribute to pathological changes such as glomerulosclerosis, tubular atrophy, and interstitial fibrosis, primarily through the activation of pro-inflammatory and pro-fibrotic signaling pathways, such as NF-B and TGF- (71)

James SH, Kimberlin DW, Whitley RJ