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Regular liver function tests are recommended during treatment.Cardiovascular Risks: It can affect cholesterol levels (increasing LDL and decreasing HDL), which may raise the risk of atherosclerosis and coronary artery disease

Data from behavioral studies using scopolamine amnesia and aged rat models, where dihexa was able to reverse cognitive deficits, indicated that the metabolic stability and BBB permeability of dihexa was apparently high enough to attain therapeutic brain levels after oral administration

In the STEP licensing trials, 3% of adults on Wegovy 2.4 mg reported hair loss, compared with 1% on placebo

Inoue A, Deem AK, Kopetz S, Heffernan TP, Draetta GF, Carugo A

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Cell Physiol Biochem 39(6):2297307 Long F, Dong C, Jiang K, Xu Y, Chi X, Sun D et al (2017) Melatonin enhances the anti-tumor effect of sorafenib via AKT/p27-mediated cell cycle arrest in hepatocarcinoma cell lines