The failure of mitochondrial steroidogenesis in GCs can result in aberrant oocyte development, especially when estrogen levels in follicular fluid are low and progesterone levels are high, affecting proper meiosis and late cleavage of oocytes (80, 102, 103)
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Another research shows that patients with minimum or mild endometriosis did not show increased levels of peritoneal and serum IL-18 [158]
It is not necessarily ruined, but it indicates the formula is degrading
10.1016/j.cotox.2017.01.006 Curr
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