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Eckburg et al., (24) used metagenomic analysis to discover the gut bacterial community is made up of six phyla: Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, Fusobacteria , and Verrucomicrobia , with the majority of the organisms in a healthy bacterial community being anaerobic population, as shown in Figure 3 (52)

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In particular, the oxidation state of two out of six cysteines controls the CAC via the formation of a disulfide bridge that switches off the transporter activity

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