Glucagon-like peptide-1 receptor agonists have demonstrated significant weight loss and cardiovascular benefits in both patients with and without diabetes, including a reduction in major adverse cardiovascular events
The Bottom Line: Transitioning Successfully Off GLP-1s Discontinuing a GLP-1 medication is a highly personal decision that should be approached with realistic expectations, thorough planning and ongoing support
Bjrnholm KD, Skovsted GF, Mitgaard-Thomsen A, Rakipovski G, Tveden-Nyborg P, Lykkesfeldt J, Povlsen GK
Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression
Fifth, we split the GLP-1 RA group into specific drug groupsliraglutide, semaglutide, exenatide, dulaglutide, and lixisenatidebased on the drug of which they had received the largest cumulative dose during the study period
Also, weight-bearing exercise strengthens bones, making them denser and stronger