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The STEP trials showed sustained weight loss maintenance when patients remained on therapy, with some individuals achieving even greater reductions through consistent dosing and lifestyle support

Salden BN, Troost FJ, de Groot E, et al

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They help lower blood sugar by stimulating insulin release, but until now it has remained unclear how they also strengthen the mitochondria, the tiny energy-producing structures that keep -cells functioning and resilient

The central hypothesis of this project is that GLP-1R and GIPR agonists selectively promote GEPNET growth depending on the expression levels of their targeted receptors

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