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Its crucial not to overdo it

138 In a randomized placebo-controlled trial in 147 women with PCOS, L-carnitine in the form of acetyl-L-carnitine (ALC), at a dosage of 500 mg twice daily, was found to add to the benefits of the anti-diabetes medications metformin and pioglitazone (Actos)

Suggested Use: As a dietary supplement, take 1-4 capsules daily, between meals

There is some theoretical basis for this thinking

The enduring effectiveness, advantageous safety profile, and supplementary metabolic advantages place these medicines as primary pharmacological choices for obesity management, especially in individuals with metabolic disorders

The article says these medications bind GLP-1 receptors on pancreatic beta cells, stimulating insulin secretion when blood glucose rises, while simultaneously signalling satiety centres in the hypothalamus to reduce appetite and slow gastric emptying