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Cell Death Dis 8:e2914 Gregoli PA, Bondurant MC (1997) The roles of Bcl-X(L) and apopain in the control of erythropoiesis by erythropoietin

Although HDACis are capable of restoring Class I-III G6PD variant activity to that of WT or greater in erythroid precursor cells, histone deacetylation is important for DNA compression, nuclear extrusion, and erythroid maturation [83-85]

Biochemical assays Inter-subunit crosslinking To apo state p97-ND1L-Cys-F360C-A413C, 4 mM DTT was added, then the solution was incubated for 2 h at 30 C

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With the nominal exception of the use of environmental sulfide for Cys biosynthesis by some chemolithotrophs (see above), this sulfide, in turn, is generated by NADPH-dependent reduction of inorganic sulfate or sulfite [131, 132]